Glykopeptide lernen mit den Eselsbrücken von Meditricks.de

Glykopeptide


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Hier eine Vorschau,
wie wir dieses Thema behandeln und wie unsere Eselsbrücken aussehen:

Glykopeptide lernen mit den Eselsbrücken von Meditricks.de

Glykopeptide

Inhaltliche Einleitung
Zu den Glykopeptidantibiotika zählen Vancomycin und Teicoplanin. Es sind Reserveantibiotika. Sie verhindern die Zellwandsynthese, wirken aber ausschließlich bei grampositiven Erregern. Vorbehalten sind sie schweren Infektionen mit Staphylokokken, inkl. MRSA, Enterokokken, Clostridien und hochresistenten Corynebakterien. Glykopeptide sind erste Wahl bei Clostridium-difficile-Infektionen und MRSA. Sie sind stark nephro- und ototoxisch.

Basiswissen

  • Grundlagen

    Glycopeptide

    Van mit glühenden Peptid-Schneeketten

  • Grundlagen

    Vancomycin und Teicoplanin

    Maus mit Mütze und die Teig-Planerin

  • Grundlagen

    Reserveantibiotika, u.a. bei MRSA/ORSA

    Konserven mit goldenen Trauben

  • Eigenschaften und Wirkmechanismus

    Glycopeptide wie Vancomycin sind große Moleküle

    Großer Van im kantigen Molekül-Look

    Ihre Größe ist für das weitere Verständnis wichtig.

  • Eigenschaften und Wirkmechanismus

    Komplexbildung mit D-Alanyl-D-Alanin (DADA): Bausteinblockade – vs. Murein-Synthese

    Van rammt Daddy Aladin im Gabelstapler mit Steinvorrat: blockiert so den Mauerbau (von lat. murus, Mauer)

    Murein ist ein Makromolekül und macht einen Großteil der bakteriellen Zellwand aus. Beta-Laktamantibiotika hemmen Enzyme, welche für die Quervernetzung der Zellwand zuständig sind. Glycopeptide blockieren dagegen die Bausteine der Zellwand.

  • ...

Expertenwissen

  • Eigenschaften und Wirkmechanismus

    Teicoplanin teils bakteriostatisch

    Teigplanerin hat Stativ

  • Eigenschaften und Wirkmechanismus

    Wg. Molekülgröße: schlecht Gewebe- und nicht Liquor-gängig

    LKWs versperren Abfahrt, transportieren gewebten Stoff und Likör

  • Wirkspektrum und Indikationen

    Nosokomiale Infekte: Pneumonie, Sepsis oder Osteomyelitis

    Krankenhauskoffer: Pneu-Money, Seppelpuppe und Markknochen

    Anwendungsbeispiele für Glycopeptide bei nosokomialen Infektionen sind: Endokarditis, Pneumonie (Pneu-Money), Sepsis (Seppelpuppe), Osteomyelitis (brennender Markknochen) sowie Wund- und Fremkörperinfektionen.

  • ...

Beginne das Lernen mit unseren Eselsbrücken,

werde Teil der Lernrevolution.


Image

Der Raub der Mona Lisa

Die Krimi-Serie rund um die neuen Antibiotika

Neu

Die 10 neuesten Meditricks:

Gereift unter der Sonne Freiburgs.    Meditricks können süchtig machen. Wir übernehmen keine Haftung für nicht mehr löschbare Erinnerungen.