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Cotrimoxazol
Die Vorsilbe “Co-” des Antibiotikums Cotrimoxazol (kurz: Cotrim) stammt aus dem Lateinischen und bedeutet 'zusammen'. Sie verweist auf die fixe Kombination von Trimethoprim (TMP) zusammen mit dem Sulfonamid Sulfamethoxazol (SMX) im Verhältnis 1:5. Cotrimoxazol wirkt gegen ein breites Spektrum an aeroben gramnegativen und grampositiven Bakterien, hierunter fallen auch einige seltene und üble nosokomiale Erreger. Außerdem wirkt Cotrim gegen den Schlauchpilz Pneumocystis jirovecii (betrifft v.a. HIV-Patienten). Doch: Es gibt viele Resistenzen und Cotrim ist fast nie Mittel der ersten Wahl, da es wirksamere Alternativen gibt.
Cotrimoxazol (Cotrim)
Koteletten-Trimmer
Cotrim ist ein Kombinationspräparat mit breitem Wirkspektrum.
Cotrim = Trimethoprim (TMP) + Sulfamethoxazol (SMX)
Tee mit MP (Maschinenpistole) + Sofa mit Ochsenhörnern (BMX)
Cotrimoxazol ist die fixe Kombination aus Trimethoprim und Sulfamethoxazolim Verhältnis 1:5 (1 Tee/MP : 5 BMX-Räder).
MdW: Pneumocystis-Pneumonie (PCP; Schlauchpilz P. jirovecii)
Erledigter Veggie-Pilz-Bösewicht (Pilz erdrosselt mit Schlauch)
Die durch P. jirovecii verursachte Pneumocystis-Pneumonie (PCP) betrifft nur immungeschwächte Patienten (Klientin im Salon im Krankenhaus).
MdW: Pneumocystis-Pneumonie Prophylaxe
Ängstlicher Bösewicht hinter lachsfarbener Tür
MdW: Nocardiose und Stenotrophomonas maltophilia
No-Cars-Schild und Stenograph mit Malzbier
Diese Infektionen betreffen vorrangig Immungeschwächte. Hier gibt es, entgegen anderer Indikationen, nur bedingt bessere Therapie-Alternativen als Cotrimoxazol.
Zweite Wahl bei Harnwegsinfekten
E-Kolibri am Katheter
2. Wahl HWIs: V.a. aufgrund zunehmender Resistenz von E. coli
Zweiter E-Kolibri bekämpft Trimmer
Prophylaxe zerebraler Toxoplasmose bei HIV-Patienten
Vor lachsfarbener Tür: Kater Gondii mit geschorenem Kopf
Cotrimoxazol dient der (Primär- und Sekundär-) Prophylaxe der zerebralen Toxoplasmose bei HIV-Patienten (AIDS-Schleife). Erreger ist Toxoplasma gondii. Hauptwirt der Toxoplasmose sind Katzen (daher Kater Gondii).
Beginne das Lernen mit unseren Eselsbrücken,
werde Teil der Lernrevolution.
Die Vorsilbe “Co-” des Antibiotikums Cotrimoxazol (kurz: Cotrim) stammt aus dem Lateinischen und bedeutet 'zusammen'. Sie verweist auf die fixe Kombination von Trimethoprim (TMP) zusammen mit dem Sulfonamid Sulfamethoxazol (SMX) im Verhältnis 1:5. Cotrimoxazol wirkt gegen ein breites Spektrum an aeroben gramnegativen und grampositiven Bakterien, hierunter fallen auch einige seltene und üble nosokomiale Erreger. Außerdem wirkt Cotrim gegen den Schlauchpilz Pneumocystis jirovecii (betrifft v.a. HIV-Patienten). Doch: Es gibt viele Resistenzen und Cotrim ist fast nie Mittel der ersten Wahl, da es wirksamere Alternativen gibt.
