Linezolid lernen mit Eselsbrücken – Drei essentielle Lernstrategien

Linezolid


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Hier eine Vorschau,
wie wir dieses Thema behandeln und wie unsere Eselsbrücken aussehen:

Linezolid lernen mit Eselsbrücken – Drei essentielle Lernstrategien

Linezolid

Inhaltliche Einleitung
Oxazolidinone wie Linezolid wirken gegen multiresistente grampositive Kokken (VRE, MRSA, MRSE und Streptokokken). Es sind Reserveantibiotika für Pneumonien, Weichteil- und Wundinfektionen. Linezolid hat teils schwere Nebenwirkungen wie die Myelosuppression. Möglich sind auch ein Serotonin-Syndrom bei der gleichzeitigen Einnahme von Psychopharmaka oder hypertensive Krisen in Wechselwirkung mit der Ernährung.

Basiswissen

  • Oxazolidinone

    Ochsen im Zoo

  • Reserveantibiotika gegen grampositive Kokken

    Konserven mit blauen Trauben

  • Linezolid

    Blaue Linie, die am Zoo liegt

  • Tedizolid

    Teddy im Zoo

  • Hemmt 50S-UE der Ribosomen → Proteinbiosynthese-Hemmung in Initiationsphase

    Am Oberkörper gefesselter Rhino-Sohn hält 50iger Schein → wollte Brot zum Füttern kaufen

    Oxazolidinone verhindern die Bildung eines funktionsfähigen Initiationskomplexes zwischen Ribosom, mRNA und tRNA (Rhino Sohn kommt erst gar nicht dazu, Proteinbrot aus dem Automaten einzulösen; das Ticket erinnert an mRNA und der Zettel an tRNA).

  • ...

Expertenwissen

  • 100% Bioverfügbarkeit → orale Gabe möglich

    Bio-Futter → füttert oral

  • Renale Elimination

    Niere entsorgt Urin der Zootiere

  • Mit Vancomycin vergleichbare Wirksamkeit und Verträglichkeit – jedoch auch wirksam bei VRE

    Van steht am Zooeingang

    Linezolid hat eine mit Vancomycin vergleichbare Wirksamkeit und Verträglichkeit. Im Unterschied zu Vancomycin wirkt Linezolid jedoch auch gegen Vancomycin-resistente Enterokokken.

  • ...

Beginne das Lernen mit unseren Eselsbrücken,

werde Teil der Lernrevolution.



Image

Der Raub der Mona Lisa

Die Krimi-Serie rund um die neuen Antibiotika

Neu

Die 10 neuesten Meditricks:

Gereift unter der Sonne Freiburgs.    Meditricks können süchtig machen. Wir übernehmen keine Haftung für nicht mehr löschbare Erinnerungen.